N'okpuru bụ okwu mmeghe nkenke gbasara usoro omume, ụdị yana nleba anya nke ihe nchekwa dị iche iche.
1.The mkpokọta mode nke omume nkeihe nchekwa
Ihe nchekwa bụ ihe ndị na-enyere aka igbu ma ọ bụ gbochie ọrụ microorganisms na ihe ịchọ mma yana idobe ogo ihe ịchọ mma n'ozuzu ya ogologo oge.
Otú ọ dị, ekwesịrị iburu n'uche na ndị na-echekwa ihe abụghị nje bacteria na ha enweghị mmetụta nje bacteria siri ike, ha na-arụkwa ọrụ naanị mgbe ejiri ya n'ụzọ zuru ezu ma ọ bụ mgbe ha na-akpakọrịta kpọmkwem na microorganisms.
Ihe nchekwa na-egbochi uto microbial na-egbochi njikọ nke enzymes metabolic dị mkpa yana igbochi njikọ nke protein na ihe ndị dị mkpa cell ma ọ bụ njikọ nke nucleic acid.
2.Ihe ndị na-emetụta Ọrụ nke Nchekwa
Ọtụtụ ihe na-enye aka na mmetụta nke ihe nchekwa.Ha gụnyere;
a.Mmetụta nke pH
Mgbanwe nke pH na-enye aka n'ịgbasa ihe nchebe nke organic acid, ya mere na-emetụta ọrụ nchekwa n'ozuzu ya.Were dịka ọmụmaatụ, na pH 4 na pH 6, 2-bromo-2-nitro-1,3-propanediol kwụsiri ike.
b.Mmetụta nke gel na ihe siri ike
Koalin, magnesium silicate, aluminom wdg, bụ ụfọdụ irighiri uzuzu na-adị ugbu a na ụfọdụ ihe ịchọ mma, nke na-ejikarị ihe nchekwa, nke na-eduga na nkwụsị nke ọrụ site na nchekwa.Otú ọ dị, ụfọdụ na-adịkwa irè n'ịnabata nje bacteria ndị dị na ihe nchekwa.Ọzọkwa, nchikota nke mmiri-soluble polymer gel na preservative na-enye aka na mbelata na ntinye nke ihe nchekwa ihe fọdụrụ na nhazi ihe ịchọ mma, nke a na-ebelatakwa mmetụta nke ihe nchekwa.
c.Mmetụta solubilization nke nonionic surfactants
Solubilization nke dị iche iche surfactants dị ka nonionic surfactants na preservatives na-emetụtakwa n'ozuzu ọrụ nke preservatives.Otú ọ dị, ihe ndị na-emepụta ihe ndị na-adịghị na-edozi mmanụ dị ka HLB = 3-6 ka amara na ha nwere ikike nkwụsịtụ dị elu na ihe nchebe ma e jiri ya tụnyere mmiri na-edozi mmiri na-edozi ahụ nke nwere uru HLB dị elu.
d.Mmetụta nke mmebi ihe nchekwa
Enwere ihe ndị ọzọ dị ka ikpo ọkụ, ọkụ wdg, bụ ndị na-akpata mmebi nke ihe nchekwa, si otú a na-eme ka mbelata mmetụta antiseptik ha.Ọzọkwa, ụfọdụ n'ime mmetụta ndị a na-eduga na mmeghachi omume biochemical n'ihi ịgba ọgwụ mgbochi radieshon na nsị.
e.Ọrụ ndị ọzọ
N'otu aka ahụ, ihe ndị ọzọ dị ka ọnụnọ nke flavors na chelating agents na nkesa nke ihe nchekwa na mmanụ-mmiri nke abụọ-phase ga-emekwa ka mbelata ọrụ nke nchekwa ruo n'ókè ụfọdụ.
3.Njirimara antiseptik nke ihe nchekwa
Njirimara antiseptik nke ihe nchekwa kwesịrị ịtụle.Inwe oke ihe nchekwa na ihe ịchọ mma ga-eme ka ọ kpasuo ya iwe, ebe ụkọ itinye uche ga-emetụta antiseptik.Njirimara nke preservatives.Ụzọ kachasị mma iji nyochaa nke a bụ iji ule ịma aka ndu nke gụnyere opekempe inhibitory itinye uche (MIC) na ule mpaghara mgbochi.
Nnwale okirikiri Bacteriostatic: A na-eji ule a chọpụta nje bacteria na ebu ndị nwere ike ito ngwa ngwa mgbe a kụrụ ya na usoro kwesịrị ekwesị.N'ọnọdụ ebe a na-atụba diski mpempe akwụkwọ nzacha nke etinyere na nchekwa n'etiti efere omenala, a ga-enwe okirikiri bacteriostatic gburugburu n'ihi ntinye nke ihe nchekwa ahụ.Mgbe ị na-atụle dayameta nke okirikiri bacteriostatic, ọ nwere ike iji dị ka yardstick iji chọpụta irè nke ihe nchekwa ahụ.
Site na nke a, enwere ike ịsị na okirikiri bacteriostatic na-eji usoro mpempe akwụkwọ na dayameta> = 1.0mm dị irè.A na-akpọ MIC dị ka ntinye ihe nchekwa kacha nta nke enwere ike itinye n'ime usoro iji gbochie uto microbial.N'ọnọdụ dị otú ahụ, obere MIC, na-esiwanye ike antimicrobial Njirimara nke preservative.
A na-egosipụtakarị ike ma ọ bụ mmetụta nke ọrụ antimicrobial n'ụdị nke kacha nta inhibitory itinye uche (MIC).Site n'ime nke a, a na-ekpebi ọrụ antimicrobial siri ike site na uru dị nta nke MIC.Ọ bụ ezie na a pụghị iji MIC mee ka ọdịiche dị n'etiti ọrụ bactericidal na bacteriostatic, ndị na-ahụ maka surfactants na-amakarị na ha nwere mmetụta bacteriostatic na obere ntinye uche na sterilization mmetụta na nnukwu ntinye uche.
N'ezie, n'oge dị iche iche, ihe omume abụọ a na-eme n'otu oge, nke a na-eme ka ha dị iche iche.N'ihi nke a, a na-enyekarị ha aha mkpokọta dị ka ọgwụ nje na-egbu nje ma ọ bụ naanị nsị.
Oge nzipu: Jun-10-2021