Dihydrocoumarin, ísì ụtọ, nke e ji mee nri dịka onye eji dochie anya cosmarin; Mpekere, aki okomoko, aki oyibo, ekpomeekpo cinnamon; A na-ejikwa ya dị ka a ụtaba.
Bụ dihydrocouman na-egbu egbu
Dihydrocoumarin abụghị ihe na-egbu egbu. Dihydrocoumarin bụ ngwaahịa ngwaahịa achọtara na Live Vanilla Rhinoceros. A kwadebere ya site na hydrogen nke di na nwunye na ọnụnọ Nickel na-achọpụta na 160-200 ℃ na nrụgide. A nwekwara ike iji ya dị ka akụrụngwa, hydrolyzed na alkaline Askaline iji mepụta o-hydroxypponponponpronion acid, akpydem, emechiri emechi.
Ọnọdụ nchekwa
Emechiri ma gbaa ọchịchịrị, echekwara na ebe dị jụụ, oghere dị na gbọmgbọm dị obere karịa ka o kwere mee n'okpuru nchekwa, ma jupụta na nchekwa nitrogen. Chekwaa na ụlọ nkwakọba ihe dị jụụ. Zere ọkụ, mmiri. Ekwesịrị ịchekwa iche iche na oxidizer, anaghị agwakọta nchekwa. Kwadebere ngwa ngwa dịgasị iche iche.
Na Citro ọmụmụ
Na vitro enzymomatic, dihydrocouman na-eme ka nsogbu na-egbochi ịta ahụhụ nke siry1 (IC50 nke 208μm). Mbelata dị na Sily1 Diagtylase doses ọbụna na micromola doses (85 ± 53 ± 13.) A na-egbochikwa microtetole SIR2 daactylase ụdị (IC50 nke 295μm).
Mgbe awa 24 nke ekpughere, Dihydrocoumarin (1-5mm) mụbara cytotoxicity na TK6 Cell ahịrị na-adabere. Dihyddrocoumarin (1-5mm) mụbao apoptosis na lines TK6 na-arụ ọrụ dabere na dose-na-adabere na awa 6. Dọnyere 5mm dose nke Dihydrocoumarin mụbaa apoptosis na oge awa 6 na TK6 Cell. Mgbe oge awa iri abụọ na anọ gasịrị, dihydrocoumarin (1-5mm) mụbara P53 Lyline 373 na 382 acentlation na-adabere na eriri nke TK6.
Post Oge: Nov-01-2024